[Teflon]

I think HDloader will only run properly formatted PS2 ISOs. But that's no problem because these days there's tools available that let you roll your own.

I've done all this to hack some PS2 game once, but I can't for the life of me remember what or why.

EDIT: oh right I use swapmagic and a moldy old PS2 which doesn't read CD-Rs no more. I was trying to get some CD-R game to run off a DVD, which is a hugely troublesome undertaking because you run face-first into the PS2's copy protection.