[q 3]

To get Knytt Stories running under Wine, you need to install msvcp60.dll (copy to the windows/system32 folder). It should work mostly okay then. There's also a Mac version of Wine but it can be rather difficult to set up. If you follow the instructions there and here you should be good to go (though you'll need to have X11 [found on the OS X install CD] and maybe also xcode tools installed first).